The combat knife is a weapon used at close-quarters, being particularly effective because of the one-hit kill slashes.
Combat Knife
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This weapon incorporates a unique clip point blade, which is flat-ground and serrated with a sinuous double curve. This design significantly amplifies the cutting power of the knife.
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—Syphon Filter 2 Weaponry Screen Description
With the knife, it doesn't matter if the target is protected with a body armor or not: getting hit by the razor-sharp blade disregards the armor and, also, the Hit Points.
This weapon is almost as effective as the grenades.
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