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Nitroglycerin, also known as nitroglycerine, trinitroglycerin (TNG), trinitroglycerine, nitro, glyceryl trinitrate (GTN), or 1,2,3-trinitroxypropane (chemical formula C3H5N3O9 ), is a heavy, colorless, oily, explosive liquid most commonly produced by nitrating glycerol with white fuming nitric acid under conditions appropriate to the formation of the nitric acid ester. Chemically, the substance is an organic nitrate compound rather than a nitro compound. However, the traditional name is often retained. Invented in 1847, nitroglycerin has been used as an active ingredient in the manufacture of explosives, mostly dynamite, and as such it is employed in the construction, demolition, and mining industries. Since the 1880s, it has been used by the military as an active ingredient, and a gelatinizer for nitrocellulose, in some solid propellants, such as cordite and ballistite.

Nitroglycerin is also a major component in double-based smokeless gunpowders used by reloaders. Combined with nitrocellulose, there are hundreds of (powder) combinations used by rifle, pistol, and shotgun reloaders.

For over 130 years, nitroglycerin has been used medically as a potent vasodilator to treat heart conditions, such as angina pectoris and chronic heart failure. Though it was previously known that these beneficial effects are due to nitroglycerin being converted to nitric oxide, a potent vasodilator, it was not until 2002 that the enzyme for this conversion was discovered to be mitochondrial aldehyde dehydrogenase. Nitroglycerin is available in sublingual tablets, sprays, and patches. Other potential suggested uses include adjunct therapy in prostate cancer.

It was used during Syphon Filter and its sequel.

Uses

Syphon Filter

Nitroglycerin was apparently used in barrels seen by Gabe Logan when he infiltrated PHARCOM warehouses. It could be shot to create a devastating explosion that killed both Logan and the enemies he encountered.

Syphon Filter 2

Gabe Logan came across vials presumably filled with nitroglycerin in the Agency's Bio Labs when he was searching for Lian Xing's vaccine, and later during the Unit One assault on the labs. He did not need them initially, but later shot them to kill the heavily armoured personnel when he could not find an effective takedown method. He employed this until he found an M-79 grenade launcher.

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